Knox played 44 snaps and spent a season-high 28 of them run blocking. He’s due a $14.568 million cap figure in 2025 and finished the 2024 season with a 22/311/1 receiving line, something that was fairly easy to foresee based on last year’s 22/186/2 line. Without Buffalo morphing into an 11-personnel team, it’s going to be hard for Knox to deliver fantasy value or, really, much value at all for the Bills in 2025. The contract suggests that unless they want to get into the world of post-June 1 moves, Knox will be around for his requisite small role in the passing offense in 2025.

With Dalton Kincaid out, this was the last chance for Knox to play himself onto the fantasy radar. However, with the Bills facing a stout Rams pass rush, Knox was used far more as a blocker than a receiver. With Kincaid likely returning next week, Knox can be cut from most fantasy rosters.

10 players registered counting stats in the box score under receiving, with Knox amassing the most yardage of the bunch. Even quarterback Josh Allen got in on the receiving fun, taking a lateral from wide receiver Amari Cooper to the house from seven yards out. Either way, Knox is unlikely to return usable counting stats consistently even with Dalton Kincaid still nursing a knee issue.

Knox has been here before. The former TE1 of the Bills found himself in a familiar role with Dalton Kincaid (knee) sidelined and made the most of his opportunity. Knox hauled in a long 24-yard pass in the second quarter that helped set up a James Cook touchdown and has now topped 40 receiving yards in three of his last four games. The Bills now head into their Week 12 bye and will return in Week 13 to face the 49ers. Assuming Kincaid is back, Knox won’t have any stand-alone value in that game.